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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 550901Generated: October 26, 2026

2-Fluorophenyl isocyanate → 3-{4-[3-(2-fluorophenyl)ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide

https://huagongshe.com/reaction/550901

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluorophenyl isocyanateHCID 85588—
Reactant3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 57445354—
Product3-{4-[3-(2-fluorophenyl)ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 57445293—

Reaction Steps

66.6 mg of solid beige-coloured 3-{4-[3-(2-fluorophenyl)ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide are prepared as described in Example 7 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide and 2-fluorophenyl isocyanate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947706B2
Source datasetuspto-grants-2011_05
ORD IDord-336e0a90429141be9a84b1e18ffb6b25
Source noteuspto-grants-2011_05