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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 550903Generated: October 26, 2026

4-(Trifluoromethyl)phenyl isocyanate → 3-{4-[3-(4-trifluoromethylphenyl)ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide

https://huagongshe.com/reaction/550903

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)phenyl isocyanateHCID 73768—
Reactant3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 57445354—
Product3-{4-[3-(4-trifluoromethylphenyl)ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 57445295—

Reaction Steps

77.6 mg of solid white 3-{4-[3-(4-trifluoromethylphenyl)ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide are prepared as described in Example 7 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide and 4-trifluoromethylphenyl isocyanate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947706B2
Source datasetuspto-grants-2011_05
ORD IDord-2a7c94533a8d400189faa4f4c7bbc845
Source noteuspto-grants-2011_05