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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 550914Generated: October 26, 2026

2-Isocyanato-1-methoxy-4-methylbenzene → 3-{4-[3-(2-methoxy-5-methylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide

https://huagongshe.com/reaction/550914

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Isocyanato-1-methoxy-4-methylbenzeneHCID 4141520—
Reactant3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 57445354—
Product3-{4-[3-(2-methoxy-5-methylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 57445306—

Reaction Steps

44.9 mg of solid beige-coloured 3-{4-[3-(2-methoxy-5-methylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide are prepared as described in Example 7 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide and 2-methoxy-5-methylphenyl isocyanate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947706B2
Source datasetuspto-grants-2011_05
ORD IDord-61c093b3e2914f80a4cf5f23f684d7e9
Source noteuspto-grants-2011_05