HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-isocyanato-2-(trifluoromethyl) benzene → 3-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-isocyanato-2-(trifluoromethyl) benzene | HCID 2733265 | — |
| Reactant | 3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide | HCID 57445354 | — |
| Product | 3-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide | HCID 57445313 | — |
Reaction Steps
29.8 mg of solid white 3-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide are prepared as described in Example 7 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide and 4-chloro-3-trifluoromethylphenyl isocyanate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07947706B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-7714206df9924d64b9dd7b23722a2b6e |
| Source note | uspto-grants-2011_05 |