4-Methylphenyl isocyanate → HCID 57445329, compound

HRID 550930Notes

Reaction equation

HRID 550930 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:16]3[C:11](=[CH:12][N:13]=[CH:14][CH:15]=3)[NH:10][C:9]=2[C:17]([NH2:19])=[O:18])=[CH:4][CH:3]=1.[C:20]1([CH3:29])[CH:25]=[CH:24][C:23]([N:26]=[C:27]=[O:28])=[CH:22][CH:21]=1>>[C:20]1([CH3:29])[CH:25]=[CH:24][C:23]([NH:26][C:27](=[O:28])[NH:1][C:2]2[CH:3]=[CH:4][C:5]([C:8]3[C:16]4[C:11](=[CH:12][N:13]=[CH:14][CH:15]=4)[NH:10][C:9]=3[C:17]([NH2:19])=[O:18])=[CH:6][CH:7]=2)=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 693254-Methylphenyl isocyanateHCID 574453513-(4-aminophenyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

Product 1

HCID 57445329HCID 57445329, compound

Procedure

76 mg of solid yellow 3-[4-(3-p-tolylureido)phenyl]-1H-pyrrolo[2,3-c]pyridine-2-carboxamide are prepared as described in Example 1 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxamide and p-tolyl isocyanate.

Sources & evidence

ORD record
ord-9041ffb8670a450ca76caac2daca5a61
Source dataset
uspto-grants-2011_05
Patent number
US07947706B2

Reaction notes

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