1-Isocyanato-3,5-dimethoxybenzene → HCID 57445335, compound

HRID 550936Notes

Reaction equation

HRID 550936 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:16]3[C:11](=[CH:12][N:13]=[CH:14][CH:15]=3)[NH:10][C:9]=2[C:17]([NH2:19])=[O:18])=[CH:4][CH:3]=1.[CH3:20][O:21][C:22]1[CH:23]=[C:24]([N:30]=[C:31]=[O:32])[CH:25]=[C:26]([O:28][CH3:29])[CH:27]=1>>[CH3:29][O:28][C:26]1[CH:25]=[C:24]([NH:30][C:31](=[O:32])[NH:1][C:2]2[CH:3]=[CH:4][C:5]([C:8]3[C:16]4[C:11](=[CH:12][N:13]=[CH:14][CH:15]=4)[NH:10][C:9]=3[C:17]([NH2:19])=[O:18])=[CH:6][CH:7]=2)[CH:23]=[C:22]([O:21][CH3:20])[CH:27]=1

Participants

3

Reactant 2

HCID 27362001-Isocyanato-3,5-dimethoxybenzeneHCID 574453513-(4-aminophenyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

Product 1

HCID 57445335HCID 57445335, compound

Procedure

87 mg of solid yellow 3-{4-[3-(3,5-dimethoxyphenyl)ureido]phenyl}-1H-pyrrolo[2,3-c]pyridine-2-carboxamide are prepared as described in Example 1 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxamide and 3,5-dimethoxyphenyl isocyanate.

Sources & evidence

ORD record
ord-7b055d366dce4ec8be0ec5184d07e964
Source dataset
uspto-grants-2011_05
Patent number
US07947706B2

Reaction notes

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