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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 550941Generated: October 25, 2026

1-Fluoro-3-isocyanato-5-(trifluoromethyl)benzene → 3-{4-[3-(3-fluoro-5-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

https://huagongshe.com/reaction/550941

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Fluoro-3-isocyanato-5-(trifluoromethyl)benzeneHCID 3445672—
Reactant3-(4-aminophenyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxamideHCID 57445351—
Product3-{4-[3-(3-fluoro-5-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-c]pyridine-2-carboxamideHCID 57445340—

Reaction Steps

69 mg of pale yellow solid 3-{4-[3-(3-fluoro-5-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-c]pyridine-2-carboxamide are prepared as described in Example 1 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxamide and 3-fluoro-5-trifluoromethylphenyl isocyanate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947706B2
Source datasetuspto-grants-2011_05
ORD IDord-6eb388b9eda44c7d92ab3c1660083c1d
Source noteuspto-grants-2011_05