HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-3-(trifluoromethyl)phenyl isocyanate → 3-{4-[3-(4-fluoro-3-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-c]pyridine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-3-(trifluoromethyl)phenyl isocyanate | HCID 2733383 | — |
| Reactant | 3-(4-aminophenyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxamide | HCID 57445351 | — |
| Product | 3-{4-[3-(4-fluoro-3-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-c]pyridine-2-carboxamide | HCID 57445341 | — |
Reaction Steps
56 mg of pale yellow solid 3-{4-[3-(4-fluoro-3-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-c]pyridine-2-carboxamide are prepared as described in Example 1 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxamide and 4-fluoro-3-trifluoromethylphenyl isocyanate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07947706B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-d8acd77a7a33458c813d7ce89203367b |
| Source note | uspto-grants-2011_05 |