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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 550943Generated: October 25, 2026

3-(Trifluoromethyl)-4-methylphenyl Isocyanate → 3-{4-[3-(4-methyl-3-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

https://huagongshe.com/reaction/550943

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)-4-methylphenyl IsocyanateHCID 3449170—
Reactant3-(4-aminophenyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxamideHCID 57445351—
Product3-{4-[3-(4-methyl-3-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-c]pyridine-2-carboxamideHCID 57445342—

Reaction Steps

61 mg of pale yellow solid 3-{4-[3-(4-methyl-3-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-c]pyridine-2-carboxamide are prepared as described in Example 1 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxamide and 4-methyl-3-trifluoromethylphenyl isocyanate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947706B2
Source datasetuspto-grants-2011_05
ORD IDord-2ff0bd48ea3d475485579f89f87c0c72
Source noteuspto-grants-2011_05