HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Nitrophenylthio)quinoline → 2-(4-Aminophenylthio)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Nitrophenylthio)quinoline | HCID 18971643 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(4-Aminophenylthio)quinoline | HCID 22637130 | 93% |
Reaction Steps
2-(4-Nitrophenylthio)quinoline (0.42 moles, 12.0 g) was hydrogenated in 300 ml DMF over 5.0 g Pd/C for 3 hr at room temperature. The solution was filtered through celite and concentrated. The product was triturated with ether and hexane to yield 2-(4-aminophenylthio)quinoline 10.0 g, 93%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05624937 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-cf4c99fe053f41b9ab5b2ac5ab6a9af3 |
| Source note | uspto-grants-1997_04 |