HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Lithium Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | N-(4-Cyanobenzyl)-L-pyroglutamic acid methyl ester | HCID 54410854 | — |
| Solvent | Oxolane--water (1/1) | HCID 21881883 | — |
| Product | Lithium Chloride | HCID 433294 | — |
| Product | N-(4-Cyanobenzyl)-L-pyroglutamic acid | HCID 22872280 | — |
Reaction Steps
N-(4-Cyanobenzyl)-L-pyroglutamic acid methyl ester (0.875 g, 0.0034 mol) was dissolved in THF:H2O (3:1) (12 mL) and treated with LiOH (0.294 g, 0.007 mol) with stirring at ambient temperature. After stirring for 3 h, the solution was neutralized with 1N HCl, and concentrated to dryness to give the title compound and 2.1 eq of LiCl which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05624936 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-f2485a4c07ac4dc0821a11680da6b71a |
| Source note | uspto-grants-1997_04 |