Thionyl Chloride → 3-methyl-4-(4-N-methyl-[1,4]diazepan-1-yl)-benzoic acid chloride

HRID 551173Notes

Reaction equation

[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N:11]1[CH2:17][CH2:16][CH2:15][N:14]([CH3:18])[CH2:13][CH2:12]1)[C:5](O)=[O:6].S(Cl)([Cl:21])=O>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N:11]1[CH2:17][CH2:16][CH2:15][N:14]([CH3:18])[CH2:13][CH2:12]1)[C:5]([Cl:21])=[O:6]

Participants

Reactant 2

HCID 24386Thionyl Chloride

HCID 621213003-methyl-4-(4-N-methyl-[1,4]diazepan-1-yl)-benzoic acid

Product 1

HCID 872489583-methyl-4-(4-N-methyl-[1,4]diazepan-1-yl)-benzoic acid chloride

Procedure

Prepared analogously to Example 29a from 3-methyl-4-(4-N-methyl-[1,4]diazepan-1-yl)-benzoic acid and thionyl chloride.

Sources & evidence

ORD record: ord-13984c04e29d4f5e80f4f572fd6a7bdb
Source dataset: uspto-grants-2011_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07947700B2

Reaction notes

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