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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 551209Generated: October 26, 2026

Diisopropylethylamine → HCID 178495743, compound

https://huagongshe.com/reaction/551209

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
Reactant3-Methyl-4-(3-oxomorpholin-4-yl)benzoic acidHCID 67048526—
Reactant(1R)-1-(5-bromo-1H-benzimidazol-2-yl)-2-methoxyethylamineHCID 178495725—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178495743HCID 178495743—

Reaction Steps

Prepared analogously to Example 1f from 3-methyl-4-(morpholin-3-on-4-yl)benzoic acid, (1R)-1-(5-bromo-1H-benzimidazol-2-yl)-2-methoxy-ethylamine, TBTU and DIPEA in THF with subsequent purification by chromatography on silica gel.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947700B2
Source datasetuspto-grants-2011_05
ORD IDord-c3aff2a346724f3286323e13dc5ca72a
Source noteuspto-grants-2011_05