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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 551219Generated: October 31, 2026

Water → 3-Chloro-4-(3,6-dihydro-[1,2]oxazin-2-yl)-benzoic acid

https://huagongshe.com/reaction/551219

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantSodium HydroxideHCID 14798—
ReactantMethyl 3-chloro-4-(3,6-dihydro-[1,2]oxazin-2-yl)-benzoateHCID 67048463—
SolventEthanolHCID 702—
Product3-Chloro-4-(3,6-dihydro-[1,2]oxazin-2-yl)-benzoic acidHCID 67048520—

Reaction Steps

Prepared analogously to Example 2d from methyl 3-chloro-4-(3,6-dihydro-[1,2]oxazin-2-yl)-benzoate and sodium hydroxide in a solvent mixture of water and ethanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947700B2
Source datasetuspto-grants-2011_05
ORD IDord-ce15051d9bfa4c838f9cb7073fac62a7
Source noteuspto-grants-2011_05