HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propylamine → 1,1,1-Trifluoro-3-{[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}-2-[(propylamino)methyl]-2-propanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propylamine | HCID 7852 | — |
| Reactant | 1-(4-fluorophenyl)-N-{[2-(trifluoromethyl)-2-oxiranyl]methyl}-indazol-4-amine | HCID 24938056 | — |
| Reactant | 3-(Ethylamino)-1,1,1-trifluoro-2-{[(1-phenyl-1H-indazol-4-yl)amino]methyl}-2-propanol | HCID 59324157 | — |
| Product | 1,1,1-Trifluoro-3-{[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}-2-[(propylamino)methyl]-2-propanol | HCID 59324137 | — |
Reaction Steps
Prepared similarly to Intermediate 15 from n-propylamine and 1-(4-fluorophenyl)-N-{[2-(trifluoromethyl)-2-oxiranyl]methyl}-1H-indazol-4-amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07947727B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-cda439db3e7744dfb1e05684bcc9c6f8 |
| Source note | uspto-grants-2011_05 |