Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 551432Generated: October 31, 2026

Propylamine → 1,1,1-Trifluoro-3-[(6-methyl-1-phenyl-1H-indazol-4-yl)amino]-2-[(propylamino)methyl]-2-propanol

https://huagongshe.com/reaction/551432

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropylamineHCID 7852—
Reactant6-Methyl-1-phenyl-N-{[2-(trifluoromethyl)-2-oxiranyl]methyl}-1H-indazol-4-amineHCID 24938055—
Reactant3-(Ethylamino)-1,1,1-trifluoro-2-{[(6-methyl-1-phenyl-1H-indazol-4-yl)amino]methyl}-2-propanolHCID 59324136—
Product1,1,1-Trifluoro-3-[(6-methyl-1-phenyl-1H-indazol-4-yl)amino]-2-[(propylamino)methyl]-2-propanolHCID 59324127—

Reaction Steps

Prepared similarly to Intermediate 18 from n-propylamine and 6-methyl-1-phenyl-N-{[2-(trifluoromethyl)-2-oxiranyl]methyl}-1H-indazol-4-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947727B2
Source datasetuspto-grants-2011_05
ORD IDord-8ad99ce477c643b9b5f74fce5749996c
Source noteuspto-grants-2011_05