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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 551435Generated: October 31, 2026

Propylamine → 1,1,1-Trifluoro-3-[(1-phenyl-1H-indazol-4-yl)amino]-2-[(propylamino)methyl]-2-propanol

https://huagongshe.com/reaction/551435

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropylamineHCID 7852—
Reactant1-Phenyl-N-{[2-(trifluoromethyl)-2-oxiranyl]methyl}-1H-indazol-4-amineHCID 24938053—
Reactant3-(Ethylamino)-1,1,1-trifluoro-2-{[(1-phenyl-1H-indazol-4-yl)amino]methyl}-2-propanolHCID 59324157—
Product1,1,1-Trifluoro-3-[(1-phenyl-1H-indazol-4-yl)amino]-2-[(propylamino)methyl]-2-propanolHCID 59324171—

Reaction Steps

Prepared similarly to Intermediate 15 from n-propylamine and 1-phenyl-N-{[2-(trifluoromethyl)-2-oxiranyl]methyl}-1H-indazol-4-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947727B2
Source datasetuspto-grants-2011_05
ORD IDord-605d1774a24740079ae607a1d3517078
Source noteuspto-grants-2011_05