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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 551442Generated: October 27, 2026

2-Methylbenzoic acid → N-Ethyl-2-methyl-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]benzamide

https://huagongshe.com/reaction/551442

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylbenzoic acidHCID 8373—
Reactant3-(Ethylamino)-1,1,1-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-propanolHCID 59324125—
ProductN-Ethyl-2-methyl-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]benzamideHCID 24937934—

Reaction Steps

Prepared similarly to Example 1 from 2-methylbenzoic acid and 3-(ethylamino)-1,1,1-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-propanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947727B2
Source datasetuspto-grants-2011_05
ORD IDord-5269b10f7e5349e9856bd21155716089
Source noteuspto-grants-2011_05