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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 551445Generated: October 31, 2026

2-Methylbenzoic acid → 2-Methyl-N-propyl-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]benzamide

https://huagongshe.com/reaction/551445

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylbenzoic acidHCID 8373—
Reactant1,1,1-Trifluoro-3-{[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}-2-[(propylamino)methyl]-2-propanolHCID 59324137—
Product2-Methyl-N-propyl-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]benzamideHCID 59324133—

Reaction Steps

Prepared similarly to Example 1 from 2-methylbenzoic acid and 1,1,1-trifluoro-3-{[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}-2-[(propylamino)methyl]-2-propanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947727B2
Source datasetuspto-grants-2011_05
ORD IDord-a19c383914094616923a2e5062902f2a
Source noteuspto-grants-2011_05