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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 551471Generated: October 27, 2026

2-Thiophenecarboxylic acid → N-Ethyl-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]-2-thiophenecarboxamide

https://huagongshe.com/reaction/551471

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiophenecarboxylic acidHCID 10700—
Reactant3-(Ethylamino)-1,1,1-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-propanolHCID 59324125—
ProductN-Ethyl-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]-2-thiophenecarboxamideHCID 59324159—

Reaction Steps

Prepared similarly to Example 1 from 2-thiophenecarboxylic acid and 3-(ethylamino)-1,1,1-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-propanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07947727B2
Source datasetuspto-grants-2011_05
ORD IDord-1140c510de15492fa96b8086aa04b7e6
Source noteuspto-grants-2011_05