反应详情

A mixture of 2.0 g of 3-methylbenzo[b]thiophene-2-acetic acid and 19.4 ml of thionyl chloride is heated at reflux for 1 hour. The volatiles are evaporated in vacuo to give a residue which is concentrated from toluene three times and dried under vacuum to give 2.25 g of the desired product as a residue.

1. temperatureis heated
2. temperatureat reflux for 1 hour
3. customThe volatiles are evaporated in vacuo
4. customto give a residue which
5. concentrationis concentrated from toluene three times
6. customdried under vacuum