1-Isopropylpiperazine → HCID 11653384, compound

HRID 551589Notes

Reaction equation

HRID 551589 reaction equation
Cl[C:2]1[CH:7]=[C:6]([C:8]([N:10]2[CH2:15][CH2:14][N:13]([CH:16]([CH3:18])[CH3:17])[CH2:12][CH2:11]2)=[O:9])[CH:5]=[CH:4][N:3]=1.Cl[C:20]1[CH:21]=[C:22]([CH:26]=[CH:27][N:28]=1)C(O)=O.[CH:29]([N:32]1CCNCC1)(C)[CH3:30]>>[CH:16]([N:13]1[CH2:14][CH2:15][N:10]([C:8]([C:6]2[CH:5]=[CH:4][N:3]=[C:2]([NH:32][CH2:29][CH2:30][N:28]3[CH2:20][CH2:21][CH2:22][CH2:26][CH2:27]3)[CH:7]=2)=[O:9])[CH2:11][CH2:12]1)([CH3:18])[CH3:17]

Participants

4

Reactant 3

HCID 780131-IsopropylpiperazineHCID 2369852-Chloroisonicotinic acidHCID 43420916(2-Chloro-pyridin-4-yl)-(4-isopropyl-piperazin-1-yl)-methanone

Product 1

HCID 11653384HCID 11653384, compound

Procedure

(2-Chloro-pyridin-4-yl)-(4-isopropyl-piperazin-1-yl)-methanone. The title compound was prepared in a manner similar to that described in Step A of Example 9 using 2-chloro-isonicotinic acid and 1-isopropyl-piperazine.

Sources & evidence

ORD record
ord-12a2bdf7a273452dbb4756f8230b793c
Source dataset
uspto-grants-2011_05
Patent number
US07947718B2

Reaction notes

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