反应详情

A solution of 2.0 g of 4-chloro-o-anisic acid in 22 ml of thionyl chloride is heated at reflux for 1 hour. The volatiles are evaporated in vacuo to give a residue which is is concentrated from toluene three times and dried under vacuum to give 2.0 g of the desired product as a residue.

1. temperatureat reflux for 1 hour
2. customThe volatiles are evaporated in vacuo
3. customto give a residue which
4. concentrationis is concentrated from toluene three times
5. customdried under vacuum