HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-benzyloxy-2-(N,N-dimethylamino)methyl-4-pyridone → 2-(N,N-dimethylamino)methyl-5-hydroxy-4-pyridone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-benzyloxy-2-(N,N-dimethylamino)methyl-4-pyridone | HCID 67748049 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(N,N-dimethylamino)methyl-5-hydroxy-4-pyridone | HCID 67748063 | 147.4% |
Reaction Steps
5-Benzyloxy-2-(N,N-dimethylamino)methyl-4-pyridone 1.0 g) in methanol (15 ml) was subjected to catalytic reduction with 10% palladium on activated carbon (200 mg) at atmospheric pressure. After removal of catalyst, the solution was concentrated under reduced pressure to give 2-(N,N-dimethylamino)methyl-5-hydroxy-4-pyridone (0.96 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05244890 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-86c329b28e3749bb825d21bed239c9be |
| Source note | uspto-grants-1993_09 |