HCID 86646138, compound → HCID 86646137, compound

Participants

Reaction Steps

Methyl 3-hydroxy-4-sec-butylhept-6-enoate (14.40 g, 67.2 mmol) was dissolved in a 2 N potassium hydroxide-methanol solution (200 mL), and the solution was stirred at room temperature for 13.5 hours. The solvent was distilled off under reduced pressure. To the residue, water and diethyl ether were then added, and the aqueous layer was neutralized with 2 N hydrochloric acid. Diethyl ether was added thereto, and the organic layer was dried over anhydrous magnesium sulfate. Then, the solvent was distilled off under reduced pressure to obtain the compound of interest as a yellow oil substance (12.70 g, 94%).

Provenance & Evidence