HCID 90884675, compound → HCID 91574392, compound

HRID 551691Notes

Reaction equation

HRID 551691 reaction equation
[C:1]([O:5][C:6](=[O:24])[CH2:7][C@@:8]1([CH2:15][NH:16][C:17]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:18])[CH2:14][C@@H:13]2[C@H:9]1[CH:10]=[CH:11][CH2:12]2)([CH3:4])([CH3:3])[CH3:2].[F:25][CH2:26][CH2:27]C1C[C@H]2[C@@H](C=1)[C@](CC(OC(C)(C)C)=O)(C[N+]([O-])=O)C2>>[C:1]([O:5][C:6](=[O:24])[CH2:7][C@@:8]1([CH2:15][NH:16][C:17]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:18])[CH2:14][C@@H:13]2[C@H:9]1[CH:10]=[C:11]([CH2:27][CH2:26][F:25])[CH2:12]2)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 90884675HCID 90884675, compoundHCID 131728923HCID 131728923, compound

Product 1

HCID 91574392HCID 91574392, compound

Procedure

The compound of interest was obtained as an oil substance (700 mg, 65.8%) in the same way as in paragraph (3-a) using tert-butyl(±)-[(1R,5S,6S)-3-(2-fluoroethyl)-6-(nitromethyl)bicyclo[3.2.0]hept-3-en-6-yl]acetate (870 mg, 2.77 mmol).

Sources & evidence

ORD record
ord-346ea0f08ee1402886cc88d3a304f475
Source dataset
uspto-grants-2011_05
Patent number
US07947738B2

Reaction notes

Loading…