Ethanol → HCID 57554555, compound

HRID 551956Notes

Reaction equation

HRID 551956 reaction equation
[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]#[C:12][C:13]2[CH:31]=[CH:30][C:16]([CH2:17][NH:18][C:19]3[CH:20]=[CH:21][C:22]([F:29])=[C:23]([CH:28]=3)[C:24]([O:26][CH3:27])=[O:25])=[CH:15][CH:14]=2)=[CH:7][CH:6]=1)[CH2:2][CH2:3][CH3:4].[CH2:32](O)[CH3:33]>>[CH2:1]([C:5]1[CH:6]=[CH:7][C:8]([C:11]#[C:12][C:13]2[CH:14]=[CH:15][C:16]([CH2:17][N:18]([CH2:32][CH3:33])[C:19]3[CH:20]=[CH:21][C:22]([F:29])=[C:23]([CH:28]=3)[C:24]([O:26][CH3:27])=[O:25])=[CH:30][CH:31]=2)=[CH:9][CH:10]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 702EthanolHCID 11452740Methyl 5-({4-[(4-butylphenyl)ethynyl]benzyl}amino)-2-fluorobenzoate

Product 1

HCID 57554555HCID 57554555, compound

Procedure

The title compound was prepared following the procedure described in Example 23 step b) using methyl 5-({4-[(4-butylphenyl)ethynyl]benzyl}amino)-2-fluorobenzoate (prepared in Example 23, step a) and ethanol. The title compound was obtained as a pale yellow oil (215 mg). HPLC, Rt: 5.8 min (purity: 98.9%).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-f3cd9bc7038a46e5bc3606708b9e9c7d
Source dataset
uspto-grants-2011_05
Patent number
US07947851B2

Reaction notes

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