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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 552058Generated: November 4, 2026

Ethanol → Ethyl 1-aminocyclopentane-1-carboxylate--hydrogen chloride (1/1)

https://huagongshe.com/reaction/552058

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantCycloleucineHCID 2901—
ReactantThionyl ChlorideHCID 24386—
ProductEthyl 1-aminocyclopentane-1-carboxylate--hydrogen chloride (1/1)HCID 302813493%

Reaction Steps

This was synthesised according to Standard Procedure 1, using 1-amino-1-cyclopentanecarboxylic acid (5.0 g, 38.6 mmol) with thionyl chloride (5.72 mL, 58 mmol) and anhydrous ethanol (29 mL). The product was isolated as a white solid (6.98 g, yield 93%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07951787B2
Source datasetuspto-grants-2011_05
ORD IDord-abe7be6ca4e0492c86db4da8cdfbc3f6
Source noteuspto-grants-2011_05