Trifluoroacetic acid → HCID 18362029, compound

Participants

Reaction Steps

To a stirred solution of 6-dibenzylamino-3-azabicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester (0.800 g, 2.10 mmol) in dichloromethane (20 mL) was added trifluoroacetic acid (2.5 mL). The resulting mixture was stirred at ambient temperature for 3 hours and then quenched with saturated aqueous solution of Na2CO3 (10 mL). The organic phase was separated, washed with water, saturated NaCl, dried over MgSO4 and then concentrated in vacuo. The obtained crude product, (3-azabicyclo[3.1.0]hex-6-yl)dibenzylamine, was used without further purification.

Provenance & Evidence