Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonium Acetate → 4,6,6-trimethyl-morpholine-3-carboxylic acid (6-chloro-9H-beta-carbolin-8-yl)-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonium Acetate | HCID 517165 | — |
| 반응물 | 6-Chloro-9H-beta-carbolin-8-amine | HCID 21362701 | — |
| 반응물 | 4,6,6-Trimethylmorpholine-3-carboxylic acid | HCID 67165462 | — |
| 생성물 | 4,6,6-trimethyl-morpholine-3-carboxylic acid (6-chloro-9H-beta-carbolin-8-yl)-amide | HCID 67166987 | 61% |
반응 단계
The desired compound was prepared according to Method B from 6-chloro-9H-β-carboline-8-ylamine and 4,6,6-trimethyl-morpholine-3-carboxylic acid in 61% yield. 1H-NMR (DMSO-d6, 300 MHz) δ 1.15 (s, 3H), 1.39 (s, 3H), 1.98 (d, 1H), 2.26 (s, 3H), 2.72 (d, 1H), 2.80 (dd, 1H), 3.79(m, 2H), 7.91 (s, 1H), 8.03-8.08 (m, 2H), 8.22 (d, 1H), 8.97 (s, 1H). Retention Time (LC, method: ammonium acetate standard): 1.33 min. MS (M+H+): 373.2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07951801B2 |
| 출처 데이터셋 | uspto-grants-2011_05 |
| ORD ID | ord-4c25266236574d33b4c75fb2002818ec |
| 출처 메모 | uspto-grants-2011_05 |