3-Fluorophenyl isocyanate → HCID 45140728, compound

Participants

Reaction Steps

Method G was used with 7-(3-aminophenoxy)-1H-imidazo[4,5-b]pyridin-2(3H)-one and 3-fluoro-phenylisocyanate to afford the title compound (10 mg, 16%). 1H-NMR (DMSO), δ (ppm), J (Hz): 6.40 (d, 1H, HPyr, J=5.9 Hz), 6.74-6.79 (m, 1H, Harom2′), 7.21 (d, 1H, Harom4 or 6, J=8.05 Hz), 7.27 (d, 1H, Harom6 or 4), 7.30-7.46 (m, 5H, Harom4′, Harom5′, Harom6′, Harom2, Harom 5), 7.79 (d, 1H, HPyr), 9.04 (s, 2H, NHurea), 11.17 (s, 1H, NHim), 11.37 (s, 1H, NHim); MS-LC, Rf=6.84 min, (C19H14FN5O3), m/z: 380.1 [M++H], 100.

Provenance & Evidence