Benzenesulfonyl chloride → HCID 45140724, compound

Participants

Reaction Steps

Method K was used with 7-(3-aminophenoxy)-1H-imidazo[4,5-b]pyridin-2(3H)-one and benzenesulfonyl chloride to afford the title compound as a brown solid (25 mg, 50%). 1H-NMR (δ, ppm, DMSO-d6): ): 6.21 (s, 1H, HPy,5), 6.77 (s, 2H, Harom), 6.95 (s, 1H, Harom), 7.29 (s, 1H, Harom), 7.53-7.86 (m, 6H, Harom), 10.44 (s, 1H, NHSO2), 11.12 (s, 1H, NHPy3), 11.39 (s, 1H, NHPy2). 13C-NMR (δ, ppm, DMSO-d6): 106.39, 110.14, 113.74, 114.64, 115.83, 126.61, 129.33, 130.82, 133.09, 139.13, 139.36, 141.25, 144.12, 147.16, 154.15, 154.97. HRMS (EI): m/z [M+H] calcd for C18H15N4O4S: 383.0814; found: 383.0815.

Provenance & Evidence