2-Methylpyrimidin-4-amine → 4-Bromo-6-methyl-pyridine-2-carboxylic acid (2-methyl-pyrimidin-4-yl)-amide
反応式
C(O[C:4]([C:6]1[CH:11]=[C:10]([Br:12])[CH:9]=[C:8]([CH3:13])[N:7]=1)=[O:5])C.[NH2:14][C:15]1[CH:20]=[CH:19][N:18]=[C:17]([CH3:21])[N:16]=1>>[CH3:21][C:17]1[N:16]=[C:15]([NH:14][C:4]([C:6]2[CH:11]=[C:10]([Br:12])[CH:9]=[C:8]([CH3:13])[N:7]=2)=[O:5])[CH:20]=[CH:19][N:18]=1参加物
3
実験手順
The tide compound, white solid, MS (ISP): m/e=307.1, 309.2 (M+H)+, was prepared from 4-Bromo-6-methyl-pyridine-2-carboxylic acid ethyl ester in accordance with the general method of example 1. Step 5 was performed using 4-Amino-2-methylpyrimidine instead of 2-Amino-4-methylthiazole.
出典と根拠
- ORDレコード
- ord-7b93c2115899417cb36da14e8b8f5ecf
- 出典データセット
- uspto-grants-2011_05
- 特許番号
- US07951824B2
反応ノート
読み込み中…