Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodopyrazine → 6-Methyl-4-pyrazin-2-yl-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodopyrazine | HCID 642841 | — |
| 반응물 | 2-Pyridinecarboxamide, 6-methyl-N-(4-methyl-2-thiazolyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)- | HCID 49760412 | — |
| 생성물 | 6-Methyl-4-pyrazin-2-yl-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide | HCID 24820879 | — |
반응 단계
The title compound, was prepared from 6-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide in accordance with the general method of example 131, step 2 using 2-iodopyrazine instead of 3-Trifluoromethyl-5-bromopyridine to yield the final compound as a white solid, MS (ISP): m/e=312.1 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07951824B2 |
| 출처 데이터셋 | uspto-grants-2011_05 |
| ORD ID | ord-8c4cbd5301b4455f8372cd737bc5f8d8 |
| 출처 메모 | uspto-grants-2011_05 |