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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 552504Generated: October 25, 2026

2-Pyridinecarboxamide, 6-methyl-N-(4-methyl-2-thiazolyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)- → HCID 24820891, compound

https://huagongshe.com/reaction/552504

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyridinecarboxamide, 6-methyl-N-(4-methyl-2-thiazolyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-HCID 49760412—
Reactant4-Bromo-6-methyl-pyridine-2-carbonitrileHCID 53485294—
ProductHCID 24820891HCID 24820891—

Reaction Steps

The title compound, was prepared from 6-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxa-borolan-2-yl)-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide in accordance with the general method of example 131, step 2 using 4-Bromo-6-methyl-pyridine-2-carbonitrile instead of 3-Trifluoromethyl-5-bromopyridine to yield the final compound as a yellow solid, MS (ISP): m/e=350.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07951824B2
Source datasetuspto-grants-2011_05
ORD IDord-2c03955bdafc45f0b84a52798be0d6a4
Source noteuspto-grants-2011_05