HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-methoxy-4-nitro-benzoyl Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Methoxy-4-nitrobenzoic acid | HCID 78764 | — |
| Solvent | 2,2,4-Trimethylpentane | HCID 10907 | — |
| Product | 3-methoxy-4-nitro-benzoyl Chloride | HCID 11127655 | — |
Reaction Steps
A stirred suspension of 1.0 g of 3-methoxy-4-nitrobenzoic acid and 1.40 ml of thionyl chloride is heated to reflux for 2 hours. The mixture is cooled to room temperature, 2 ml of iso-octane added and the mixture evaporated in vacuo to a solid residue. The residue is washed with iso-octane (2×2 ml), dried in vacuo to give 1.08 g of cream colored solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05624923 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-7bbacb0f150a4f3597ed06de4962c7f0 |
| Source note | uspto-grants-1997_04 |