化工社化工社 化学情報印刷レポート · 研究参考用
4-Bromo-2-methylpyridine → 6,2'-Dimethyl-[4,4']bipyridinyl-2-carboxylic acid (2-chloro-pyridin-4-yl)-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Bromo-2-methylpyridine | HCID 2762835 | — |
| 反応物 | N-(2-Chloropyridin-4-yl)-6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxamide | HCID 49760409 | — |
| 生成物 | 6,2'-Dimethyl-[4,4']bipyridinyl-2-carboxylic acid (2-chloro-pyridin-4-yl)-amide | HCID 86614585 | — |
反応手順
The title compound, was prepared from 6-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine-2-carboxylic acid (2-chloro-pyridin-4-yl)-amide in accordance with the general method of example 131, step 2 using 4-Bromo-2-methylpyridine instead of 3-Trifluoromethyl-5-bromopyridine to yield the final compound as a white solid, MS (ISP): m/e=339.1, 341.1 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07951824B2 |
| 出典データセット | uspto-grants-2011_05 |
| ORD ID | ord-b34e615da9dd47bf8810bf77aa74ebb9 |
| 出典メモ | uspto-grants-2011_05 |