HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-methylpyridine → 6,2'-Dimethyl-[4,4']bipyridinyl-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-methylpyridine | HCID 2762835 | — |
| Reactant | 2-Methyl-6-((1-methyl-1H-pyrazol-3-yl)carbamoyl)pyridine-4-boronic acid pinacol ester | HCID 67163979 | — |
| Product | 6,2'-Dimethyl-[4,4']bipyridinyl-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide | HCID 24820958 | — |
Reaction Steps
The title compound, was prepared from 6-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide in accordance with the general method of example 131, step 2 using 4-Bromo-2-methylpyridine instead of 3-Trifluoromethyl-5-bromopyridine to yield the final compound as a white amorphous, MS (ISP): m/e=308.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951824B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-ffa48d76df2e46a199288857165f1b15 |
| Source note | uspto-grants-2011_05 |