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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 552532Generated: October 31, 2026

1-Methyl-3-aminopyrazole → 6-Methyl-4-pyrimidin-5-yl-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide

https://huagongshe.com/reaction/552532

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-3-aminopyrazoleHCID 137254—
Reactant6-Methyl-4-pyrimidin-5-yl-pyridine-2-carboxylic acid ethyl esterHCID 67164418—
Product6-Methyl-4-pyrimidin-5-yl-pyridine-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amideHCID 24820979—

Reaction Steps

The title compound, was prepared from 6-Methyl-4-pyrimidin-5-yl-pyridine-2-carboxylic acid ethyl ester in accordance with the general method of example 26, step 6 using 3-Amino-1-methylpyrazole instead of 3-chloroaniline to yield the final compound as a gray crystalline, MS (ISP): m/e=295.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07951824B2
Source datasetuspto-grants-2011_05
ORD IDord-87584020a02240ce95eb2ccf3c6fbb4e
Source noteuspto-grants-2011_05