HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-chloropyridine → 5-Fluoro-6'-methyl-[3,4']bipyridinyl-2'-carboxylic acid (5-chloro-pyridin-2-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-chloropyridine | HCID 66174 | — |
| Reactant | 5-Fluoro-6'-methyl-[3,4']bipyridinyl-2'-carboxylic acid ethyl ester | HCID 67164770 | — |
| Product | 5-Fluoro-6'-methyl-[3,4']bipyridinyl-2'-carboxylic acid (5-chloro-pyridin-2-yl)-amide | HCID 67164401 | — |
Reaction Steps
The title compound, was prepared from 5-Fluoro-6′-methyl-[3,4′]bipyridinyl-2′-carboxylic acid ethyl ester in accordance with the general method of example 26, step 6 using 2-Amino-5-chloropyridine instead of 3-chloroaniline to yield the final compound as a white solid, MS (ISP): m/e=343.1, 345.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951824B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-e84ec8b15e5a4fc3b418105fb1f2736f |
| Source note | uspto-grants-2011_05 |