3-Chloroaniline → HCID 67163826, compound

HRID 552536Notes

Reaction equation

HRID 552536 reaction equation
C(O[C:4]([C:6]1[CH:11]=[C:10]([C:12]2[CH:13]=[N:14][CH:15]=[C:16]([F:18])[CH:17]=2)[CH:9]=[C:8]([CH3:19])[N:7]=1)=[O:5])C.[Cl:20][C:21]1[CH:22]=[C:23]([CH:25]=[CH:26][CH:27]=1)[NH2:24]>>[Cl:20][C:21]1[CH:22]=[C:23]([NH:24][C:4]([C:6]2[CH:11]=[C:10]([C:12]3[CH:13]=[N:14][CH:15]=[C:16]([F:18])[CH:17]=3)[CH:9]=[C:8]([CH3:19])[N:7]=2)=[O:5])[CH:25]=[CH:26][CH:27]=1

Participants

3

Reactant 2

HCID 79323-ChloroanilineHCID 671647705-Fluoro-6'-methyl-[3,4']bipyridinyl-2'-carboxylic acid ethyl ester

Product 1

HCID 67163826HCID 67163826, compound

Procedure

The title compound, was prepared from 5-Fluoro-6′-methyl-[3,4′]bipyridinyl-2′-carboxylic acid ethyl ester in accordance with the general method of example 26, step 6 using 3-Chloroaniline instead of 3-chloroaniline to yield the final compound as a white solid, MS (ISP): m/e=342.0, 344.1 (M+H)+.

Sources & evidence

ORD record
ord-6716c3682eee499bb1443499f6efdc3f
Source dataset
uspto-grants-2011_05
Patent number
US07951824B2

Reaction notes

Loading…