HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-1,1,1-trifluorobutane → (2-(S)-Pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-[4-(4,4,4-trifluoro-butoxy)-phenyl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-1,1,1-trifluorobutane | HCID 521006 | — |
| Reactant | (4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone | HCID 11960316 | — |
| Product | (2-(S)-Pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-[4-(4,4,4-trifluoro-butoxy)-phenyl]-methanone | HCID 11960424 | — |
Reaction Steps
The title compound is prepared in a manner substantially analogous to Procedure E except the reaction mixture is stirred at room temperature overnight starting from (4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone and 1-bromo-4,4,4-trifluorobutane. MS (ES+) 385.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951826B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-2a92b8d74c6e4c7dbc9e0164db651fa0 |
| Source note | uspto-grants-2011_05 |