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HRID 552587作成日:2026年10月25日

Pentane, 1-bromo-5-fluoro- → [4-(5-Fluoro-pentyloxy)-phenyl]-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone

https://huagongshe.com/reaction/552587

反応式

関与物質

役割名称HCID仕込み量
反応物Pentane, 1-bromo-5-fluoro-HCID 120236—
反応物(4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanoneHCID 11960316—
生成物[4-(5-Fluoro-pentyloxy)-phenyl]-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanoneHCID 11960423—

反応手順

The title compound is prepared in a manner substantially analogous to Procedure E except the reaction mixture is stirred at room temperature overnight starting from (4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone and 1-bromo-5-fluoropentane. MS (ES+) 363.3

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07951826B2
出典データセットuspto-grants-2011_05
ORD IDord-542b93e61a6c415a8f49ad895ea8364e
出典メモuspto-grants-2011_05