HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 3-oxopyrrolidine-1-carboxylate → 1-Pyrrolidinecarboxylic acid, 3-hydroxy-3-(2-methylphenyl)-, 1,1-dimethylethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 3-oxopyrrolidine-1-carboxylate | HCID 471360 | — |
| Reactant | HCID 178424303 | HCID 178424303 | — |
| Product | 1-Pyrrolidinecarboxylic acid, 3-hydroxy-3-(2-methylphenyl)-, 1,1-dimethylethyl ester | HCID 59030476 | — |
Reaction Steps
Prepared in analogy to Example A1 (a) from N-boc-3-pyrrolidinone and o-tolyl-magnesiumbromide to yield the title compound as an light yellow oil. MS (m/e): 278.2 (M+H+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951836B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-a0185d0402964f88a4a4296f1f97ab23 |
| Source note | uspto-grants-2011_05 |