HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 552741Generated: October 31, 2026
Phenyl isocyanate → HCID 67164847, compound
https://huagongshe.com/reaction/552741
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Phenyl isocyanate | HCID 7672 | — |
| Reactant | 5'-o-Acetyl-2',3'-o-isopropylideneadenosine | HCID 85167 | — |
| Solvent | 2-Oxopropiononitrile | HCID 69430 | — |
| Product | HCID 67164847 | HCID 67164847 | 100% |
Reaction Steps
To a solution of [(3aR,4R,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl]methyl acetate (0.200 g, 0.572 mmol) in AcCN (3 mL) was added phenylisocyanate (0.068 g, 0.572 mmol) dropwise. The white mixture was stirred for two hours at ambient temperature, overnight at 50° C. and then concentrated to give the title compound (0.268 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07951810B2 |
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| Source dataset | uspto-grants-2011_05 |
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| ORD ID | ord-342fb363225848a68ee899e08241be57 |
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| Source note | uspto-grants-2011_05 |
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