HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1E)-6-bromo-1-(4-methoxyphenyl)-1-hexene → HCID 19957426, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1E)-6-bromo-1-(4-methoxyphenyl)-1-hexene | HCID 15472944 | — |
| Reactant | HCID 19957432 | HCID 19957432 | — |
| Product | HCID 19957426 | HCID 19957426 | 50.3% |
Reaction Steps
Under the conditions of example 1 D, 440 mg of 3-(6-tert-butoxycarbonyl-3-hydroxy-2-pyridyl)-propionic acid-tert-butyl ester is reacted with 367 mg of (1E)-6-bromo-1-(4-methoxyphenyl)-1-hexene, worked up, and the crude product is chromatographed on silica gel with hexane/0-8% ethyl acetate. 350 mg of 3-{6-tert-butoxycarbonyl-3-[6-(4-methoxyphenyl)-(5E)-5-hexenyloxy]-2-pyridyl}-propionic acid-tert-butyl ester is obtained as oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05624943 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-577d5dfb64c542c4bf4eb8a00cefcd42 |
| Source note | uspto-grants-1997_04 |