HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetraethyl orthocarbonate → 2-Ethoxy-6-hydroxybenzoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetraethyl orthocarbonate | HCID 66213 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 4-Aminobenzene-1,3-diol hydrochloride | HCID 13408822 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Ethoxy-6-hydroxybenzoxazole | HCID 21077799 | 60% |
Reaction Steps
A mixture of equivalent amounts of 4-aminoresorcinol hydrochloride and anhydrous sodium acetate in anhydrous ethanol was stirred for 16 hours at room temperature with a slight excess of tetraethyl orthocarbonate to give 2-ethoxy-6-hydroxybenzoxazole in 60% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951955B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-ec688fd7354244d8adb77fb55d114b1a |
| Source note | uspto-grants-2011_05 |