HRID553023

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1049

Pyridine

C5H5N

结构：CC[N+]1=C(C)C(C)(CCCC(=O)O)c2ccccc21.[I-]

HCID67164042

未命名化合物

结构：CC1(CCCS(=O)(=O)O)C(/C=C/Nc2ccccc2)=[N+](CCCS(=O)(=O)O)c2ccccc21.[Na+]

HCID86639981

未命名化合物

PRODUCTS

生成物

结构：CCN1/C(=C/C=C/C2=[N+](CCCS(=O)(=O)O)c3ccccc3C2(C)CCCS(=O)(=O)O)C(C)(CCCC(=O)O)c2ccccc21.[Na+]

HCID131728941

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID176

Acetic Acid

C2H4O2

溶剂HCID7918

Acetic anhydride

C4H6O3

PROCEDURE

实验过程

500 mg (1 mmol) 1-ethyl-3-methyl-2-((E)-2-phenylamino-vinyl)-5-sulfo-3-(3-sulfo-propyl)-3H-indolium sodium salt 8 and 387 mg (1 mmol) 3-(3-carboxypropyl)-2,3-dimethyl-1-ethyl-3H-indolium iodide salt 3 are dissolved in a mixture of 10 ml acetic acid and 10 ml acetic anhydride. Subsequently, 5 ml of pyridine is added. The solution is stirred under reflux for 15 minutes.

WORKUP

后处理

temperatureunder reflux for 15 minutes

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-13ce02a4c0624d9281257dbd3cf34795
来源数据集: uspto-grants-2011_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07951959B2
来源说明: uspto-grants-2011_05

反应 SMILES

[Na+:1].[CH3:2][C:3]1([CH2:28][CH2:29][CH2:30][S:31]([OH:34])(=[O:33])=[O:32])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N+:5]([CH2:12][CH2:13][CH2:14][S:15]([OH:18])(=[O:17])=[O:16])=[C:4]1/[CH:19]=[CH:20]/NC1C=CC=CC=1.[I-].[C:36]([CH2:39][CH2:40][CH2:41][C:42]1([CH3:54])[C:50]2[C:45](=[CH:46][CH:47]=[CH:48][CH:49]=2)[N+:44]([CH2:51][CH3:52])=[C:43]1[CH3:53])([OH:38])=[O:37].N1C=CC=CC=1>C(O)(=O)C.C(OC(=O)C)(=O)C>[Na+:1].[C:36]([CH2:39][CH2:40][CH2:41][C:42]1([CH3:54])[C:50]2[C:45](=[CH:46][CH:47]=[CH:48][CH:49]=2)[N:44]([CH2:51][CH3:52])/[C:43]/1=[CH:53]/[CH:20]=[CH:19]/[C:4]1[C:3]([CH3:2])([CH2:28][CH2:29][CH2:30][S:31]([OH:34])(=[O:32])=[O:33])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N+:5]=1[CH2:12][CH2:13][CH2:14][S:15]([OH:18])(=[O:16])=[O:17])([OH:38])=[O:37]