HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrabutylammonium Fluoride → N-(3-ethynylphenyl)-1,1,1-trifluoromethanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| Reactant | N-[3-(2-trimethylsilylethinyl)-phenyl]-1,1,1-trifluoromethanesulfonamide | HCID 19957475 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-(3-ethynylphenyl)-1,1,1-trifluoromethanesulfonamide | HCID 19957419 | 25% |
Reaction Steps
Under the conditions of example 21 C, 2 g of N-[3-(2-trimethylsilylethinyl)-phenyl]-1,1,1-trifluoromethanesulfonamide is reacted with 6.9 ml of a 1-molar solution of tetrabutylammonium fluoride in tetrahydrofuran and worked up. 387 mg of N-(3-ethinylphenyl)-1,1,1-trifluoromethanesulfonamide is obtained as oily crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05624943 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-c1ebe54cd5b54babae77f5eaa3a4f56b |
| Source note | uspto-grants-1997_04 |