1-(tert-Butoxycarbonyl)-4-(methanesulfonyloxy)piperidine → HCID 18969307, compound

HRID 553086Notes

Reaction equation

HRID 553086 reaction equation
[N+:1]([C:4]1[N:5]=[CH:6][NH:7][CH:8]=1)([O-:3])=[O:2].[C:9]([O:13][C:14]([N:16]1[CH2:21][CH2:20][CH:19](OS(C)(=O)=O)[CH2:18][CH2:17]1)=[O:15])([CH3:12])([CH3:11])[CH3:10]>>[C:9]([O:13][C:14]([N:16]1[CH2:21][CH2:20][CH:19]([N:7]2[CH:8]=[C:4]([N+:1]([O-:3])=[O:2])[N:5]=[CH:6]2)[CH2:18][CH2:17]1)=[O:15])([CH3:12])([CH3:10])[CH3:11]

Participants

3

Reactant 2

HCID 41848691-(tert-Butoxycarbonyl)-4-(methanesulfonyloxy)piperidineHCID 178526856HCID 178526856, compound

Product 1

HCID 18969307HCID 18969307, compound

Procedure

4-nitroimidazole was alkylated with 4-methanesulfonyloxy-piperidine-1-carboxylic acid tert-butyl ester to provide the title compound: C13 NMR (100 MHz, CDCl3) 28.5, 33.2, 42.7, 56.8, 80.7, 117.5, 134.4, 154.5; MS 297.1 m/z (M+1).

Sources & evidence

ORD record
ord-8f56e10cc94d458f9c7e6ed14606f488
Source dataset
uspto-grants-2011_05
Patent number
US07951958B2

Reaction notes

Loading…